From what I've worked out so far, the use of St Vincent's name around so much of Bristol, especially Hotwells and Clifton, dervies from the ancient hermitage and chapel dedicated to St Vincent of Saragossa, which (possibly) was in Ghyston’s Cave, the cave in the rock face now accessible through a tunnel from the observatory, but at the time only by a perilous cliff climb (which I can only presume is what made it so appropriate for a hermitage.)
Why St Vincent of Saragossa? Anthony Adolph says:
It should be explained that the connection of Bristol with the Iberian wine trade led, in the Middle Ages, to Bristol’s importing of the cult of Lisbon’s patron saint, Vincent.
I have done very little real research on this so far, though, so don't take my word for any of it. I am not a historian, etc.
GPS Coordinates:
51.45189, -2.61946
Location: Hotwells